Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor α (TNF-α) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-κB) Signaling Pathway.

Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor α (TNF-α) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-κB) Signaling Pathway.

BACKGROUND quercetin (Que) reported to induce apoptosis of lung cancer cells. Src is closely related to the development of lung cancer is non-small cell (NSCLC) and can be affected by Que in macrophages. In this study, the interaction between Que and Src signaling in NSCLC cell NSCLC explored to explain the anti-function Que.

MATERIALS AND METHODS HCC827 NSCLC cell lines were subjected to administration of Que at different concentrations. Que influence on tumor cell proliferation was detected using MTT and colony formation test. Then the effect on the migration and invasion ability was assessed using the initial and Transwell test. At the molecular level, changes in Src / Fn14 / NF-kappaB signaling is determined using western blotting tests.

The role of Src in Que function further explored by inducing the expression of Src gene in NSCLC cells prior to administration Que. The test results were verified in vitro using a mouse model of NSCLC. RESULTS Que inhibits the proliferation and anchorage-independent cell growth in NSCLC. Additionally, Que delayed in closing a gap in the level of initial tests and a decrease in the number of cells in the membrane-penetrating Transwell test. At the molecular level, Que suppressed the expression of Src, which then inhibit Fn14 / NF-kappaB signaling.

In in vivo tests, Que inhibits the growth of solid tumors. After the excess of Src in NSCLC cells, the effect of anti-NSCLC NSCLC Que blocked by inducing the proliferation and metastasis, and by activating Fn14 / NF-kappaB signaling. In addition, the induced levels of Src promoted the growth and metastatic potential of solid tumors in mice. CONCLUSION Que anti-NSCLC given effect by inhibiting Src-mediated Fn14 / NF-kappaB pathway both in vitro and in vivo.

Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor α (TNF-α) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-κB) Signaling Pathway.
Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor α (TNF-α) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-κB) Signaling Pathway.

Osteoarthritis Prevented in Mice by Verbascoside via Nuclear Factor kappa B (NF-kB) Downregulation Pathway.

BACKGROUND Cartilage degeneration for osteoarthritis (OA), the most adversely affects the quality of life by inhibiting the movement. This study investigated the verbascoside role in the protection of cartilage degeneration caused by osteoarthritis. MATERIALS AND METHODS enzyme-linked immunosorbent assay (ELISA) and western blot test is used to determine the secretion of inflammatory cytokines in serum and cartilage tissue, respectively.

RESULTS Treatment of the mice with excess verbascoside OA inhibiting interleukin (IL) -6, tumor necrosis factor (TNF) -alpha, and IL-1SS in serum and cartilage tissue.

P2X7R expression and matrix metalloproteinase (MMP) -13 is much higher in mice induced by OA. However, the administration reversed verbascoside OA-induced upregulation of P2X7R and MMP-13 expression in cartilage tissue. OA-mediated increase in substance P (SP) and prostaglandin E2 (PGE2) expression was also reduced in cartilage tissue by verbascoside treatment. Western blot assay revealed that treatment verbascoside IkappaBalpha markedly decreased activation of NF-kappaB and p65 in mice OA.

CONCLUSION So, verbascoside inhibits the secretion of inflammatory cytokines in rats OA by targeting P2X7R expression, the production of matrix metalloproteinases, PGE2 and downregulation of NF-kappaB signaling pathway. Therefore, verbascoside can be used as an effective agent for the treatment of osteoarthritis.

The Onco-suppressor p53 is a transcription factor that regulates a broad spectrum of genes involved in various cellular functions including apoptosis, cell cycle arrest, senescence, autophagy, DNA repair and angiogenesis. p53 and NF-kB generally has the opposite effect on the cancer cells.

Kappa Light Chain (Kappa-IgLC) Antibody

abx415799-05mg 0.5 mg
EUR 477.6

Kappa Light Chain (Kappa-IgLC) Antibody

abx411144-1mg 1 mg
EUR 661.2

Kappa Light Chain (Kappa-IgLC) Antibody

abx411421-1ml 1 ml
EUR 526.8

Kappa Light Chain (Kappa-IgLC) Antibody

abx411422-05mg 0.5 mg
EUR 794.4

Kappa Light Chain (Kappa-IgLC) Antibody

abx412052-1ml 1 ml
EUR 526.8

Kappa Light Chain (Kappa-IgLC) Antibody

abx413125-1mg 1 mg
EUR 994.8

KAPPA/LAMBDA

1KF3LPE2-50T 50 test
EUR 806.46

Kappa Antibody

P1045-01m 0.1m
EUR 163.2

Kappa Antibody

P1045-1ml 1ml
EUR 337.2

KAPPA/CD19

KAPPAF219PE1-50T 50 test
EUR 420.36

KAPPA/LAMBDA

KAPPAF2LAMBDAPE-50T 50 test
EUR 496.8

KAPPA/CD19

KF319PE4-50T 50 test
EUR 559.2

LAMBDA/KAPPA

LF2KPE3-50T 50 test
EUR 738.6

Kappa (NFKB1)

MO47031 100 ul
EUR 418.8

kappa-Carrageenan

GC6839-100G 100 g
EUR 74.4

kappa-Carrageenan

GC6839-1KG 1 kg
EUR 270

kappa-Carrageenan

GC6839-250G 250 g
EUR 112.8

kappa-Carrageenan

GC6839-25G 25 g
EUR 51.6

kappa-Carrageenan

GC6839-500G 500 g
EUR 170.4

Human Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670165-1mg 1 mg
EUR 560.4

Human Immunoglobulin G2 Kappa (IgG2 Kappa) Protein

abx670166-1mg 1 mg
EUR 627.6

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx414986-05mg 0.5 mg
EUR 861.6

Kappa Light Chain (Kappa-IgLC) Antibody (FITC)

abx415784-1mg 1 mg
EUR 560.4

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx415785-1ml 1 ml
EUR 594

Kappa Light Chain (Kappa-IgLC) Antibody (Biotin)

abx415787-05mg 0.5 mg
EUR 560.4

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx415788-1ml 1 ml
EUR 594

Kappa Light Chain (Kappa-IgLC) Antibody (RPE)

abx415789-05ml 0.5 ml
EUR 760.8

Kappa Light Chain (Kappa-IgLC) Antibody (FITC)

abx411143-05mg 0.5 mg
EUR 526.8

Kappa Light Chain (Kappa-IgLC) Antibody (TRITC)

abx411145-05mg 0.5 mg
EUR 744

Kappa Light Chain (Kappa-IgLC) Antibody (AP)

abx411146-1ml 1 ml
EUR 678

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx411147-1ml 1 ml
EUR 594

Kappa Light Chain (Kappa-IgLC) Antibody (Biotin)

abx411149-1mg 1 mg
EUR 727.2

Kappa Light Chain (Kappa-IgLC) Antibody (RPE)

abx411150-025mg 0.25 mg
EUR 760.8

Kappa Light Chain (Kappa-IgLC) Antibody (AP)

abx411216-1ml 1 ml
EUR 678

Kappa Light Chain (Kappa-IgLC) Antibody (Biotin)

abx411218-1mg 1 mg
EUR 594

Kappa Light Chain (Kappa-IgLC) Antibody (RPE)

abx411219-05mg 0.5 mg
EUR 910.8

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx412923-05mg 0.5 mg
EUR 861.6

Kappa Light Chain (Kappa-IgLC) Antibody (HRP)

abx413129-01mg 0.1 mg
EUR 594

Human Kappa Light Chain (Kappa-IgLC) Protein

abx670245-1mg 1 mg
EUR 661.2

Human Kappa Light Chain (Kappa-IgLC) Protein

abx670246-1mg 1 mg
EUR 777.6

Mouse Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670291-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin G2a Kappa (IgG2a Kappa) Protein

abx670292-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin G2b Kappa (IgG2b Kappa) Protein

abx670293-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin M Kappa (IgM Kappa) Protein

abx670294-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin E Kappa (IgE Kappa) Protein

abx670299-05mg 0.5 mg
EUR 727.2

Human Kappa Light Chain (Kappa-IgLC) ELISA Kit

abx055741-96tests 96 tests
EUR 801.6

Kappa Light Chain (Kappa-IgLC) Antibody (Texas Red)

abx411148-05mg 0.5 mg
EUR 744

Kappa Light Chain (Kappa-IgLC) Antibody (Texas Red)

abx411217-1mg 1 mg
EUR 560.4

PTP kappa antibody

70R-50295 100 ul
EUR 292.8
Description: Purified Polyclonal PTP kappa antibody

Kappa actin antibody

70R-51228 100 ul
EUR 292.8
Description: Purified Polyclonal Kappa actin antibody

Mouse IgM Kappa

31R-1091 100 ug
EUR 207.6
Description: Purified Mouse IgM Kappa Isotype Control

RBPJ kappa antibody

70R-13485 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal RBPJ kappa antibody

Kappa Light Chain

10R-8329 100 ug
EUR 318
Description: Mouse monoclonal Kappa Light Chain antibody

DGK kappa Antibody

20-abx133186
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

kappa actin Antibody

20-abx007912
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

PTP kappa Antibody

20-abx008797
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

IgA kappa Protein

abx060686-1mg 1 mg
EUR 777.6

Kappa Light Chain

A20064 2 ml
EUR 94.8

KAPPA Antibody (FITC)

abx200536-100tests 100 tests
EUR 828

KAPPA Antibody (PE)

abx200537-100tests 100 tests
EUR 1011.6

KAPPA Antibody (FITC)

abx200538-100tests 100 tests
EUR 727.2

KAPPA Antibody (PE)

abx200539-100tests 100 tests
EUR 727.2

KAPPA Antibody (APC)

abx201104-100tests 100 tests
EUR 777.6

Kappa Light Chain

A00064 6 ml
EUR 129.6

Kappa Light Chain

A00064.0025 25 ml
EUR 302.4

KAPPA/LAMBDA/CD19

KAPPAF2LAMBDAPE19PC2-50T 50 test
EUR 941.4

Kappa Opioid Receptor

MO15098 100 ug
EUR 459.6

Kappa Opioid Receptor

RA10103T 50 ul
EUR 212.4

Anti-Kappa antibody

STJ160049 1 mL C
EUR 282
Description: Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas, where the expression of a single light chain class is restricted. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining of kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins.

Anti-Kappa antibody

STJ180139 0.1 ml
EUR 254.4

Anti-Kappa antibody

STJ180388 0.1 ml
EUR 254.4

IgG2a-Kappa Antibody

R20165-100UG 100ug
EUR 409

IgG2a-Kappa Antibody

R20165BTN-50UG 50ug
EUR 409

IgG2a-Kappa Antibody

R20165SAF-250UG 250ug
EUR 979

Kappa/Lambda Light Chain (Kappa/Lambda-IgLC) Antibody (HRP)

abx412924-05mg 0.5 mg
EUR 1028.4

Kappa casein ELISA Kit| Bovine Kappa casein ELISA Kit

EF011008 96 Tests
EUR 826.8

Kappa light chain Antibody

DF13703 100ul
EUR 420

Human Kappa ELISA Kit

E-80KPA 1 x 96 well plate
EUR 529.2

anti- immunoglobulin kappa antibody

FNab04295 100µg
EUR 658.5
Description: Antibody raised against immunoglobulin kappa

Kappa Light chain Antibody

46588-100ul 100ul
EUR 302.4

Kappa Opioid Receptor Antibody

47902-100ul 100ul
EUR 302.4

Human IgE Kappa protein

31C-CP1035K 100 ug
EUR 547.2
Description: Purified Human IgE Kappa protein

Human IgM Kappa protein

31R-AI088S 1 mg
EUR 159.6
Description: Purified Human IgM Kappa protein

Anti-Actin- kappa Antibody

A14672-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Actin- kappa Antibody (ACTBL2) detection. Tested with WB in Human, Mouse.

Kappa Light Chain (HRP)

10R-8330 100 ug
EUR 338.4
Description: Mouse monoclonal Kappa Light Chain antibody (HRP)

IgG kappa chain antibody

10-1935 200 ul
EUR 651.6
Description: Mouse monoclonal IgG kappa chain antibody

Mouse IgM, kappa Protein

abx160025-1mg 1 mg
EUR 844.8

Casein Kappa (CSN3) Antibody

20-abx171599
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Casein Kappa (CSN3) Antibody

20-abx171600
  • EUR 1178.40
  • EUR 594.00
  • 1 mg
  • 200 ug

Immunoglobulin kappa Protein (OVA)

20-abx165553
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

DGK kappa Blocking Peptide

20-abx161835
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

kappa Opioid Receptor Antibody

20-abx121635
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Immunoglobulin Kappa (Igk) Antibody

20-abx132190
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Kappa light chains Antibody

abx140224-01mg 0.1 mg
EUR 427.2

Kappa light chains Antibody

abx140234-01mg 0.1 mg
EUR 427.2

Kappa light chains Antibody

abx140262-01mg 0.1 mg
EUR 460.8

Casein Kappa (CSN3) Antibody

20-abx130922
  • EUR 577.20
  • EUR 159.60
  • EUR 1680.00
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Casein Kappa (CSN3) Antibody

20-abx129181
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

kappa Light Chains Antibody

abx023821-1mg 1 mg
EUR 718.8

Mouse IgG1 kappa Protein

abx060692-1mg 1 mg
EUR 627.6

Mouse IgM kappa Protein

abx060693-1mg 1 mg
EUR 794.4

Human IgG2 kappa Protein

abx060993-1mg 1 mg
EUR 460.8

Human IgG4 kappa Protein

abx060995-1mg 1 mg
EUR 678

Mouse IgG2a, kappa Protein

abx061466-1mg 1 mg
EUR 861.6

PTP kappa Blocking Peptide

20-abx063170
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

kappa actin Blocking Peptide

20-abx064103
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

kappa light chain Antibody

abx025345-400ul 400 ul
EUR 627.6

kappa light chain Antibody

abx025345-80l 80 µl
EUR 343.2

Kappa Casein (CSN3) Antibody

abx232019-100ug 100 ug
EUR 577.2

Immunoglobulin Kappa (Igk) Antibody

20-abx270090
  • EUR 594.00
  • EUR 693.60
  • EUR 343.20
  • EUR 1062.00
  • EUR 444.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Immunoglobulin Kappa (Igk) Antibody

20-abx176921
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug

Immunoglobulin Kappa (Igk) Antibody

20-abx176922
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Immunoglobulin Kappa (Igk) Antibody

20-abx176923
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interferon Kappa (IFNk) Antibody

20-abx177045
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Interferon Kappa (IFNK) Antibody

20-abx216271
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

NFR kappa B Antibody

20-abx217161
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Anti-PP2C kappa Antibody

A04319 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for PP2C kappa Antibody (PPM1K) detection.tested for WB in Human.

Kappa; Clone L1C1 (Concentrate)

A00113-C 1 ml
EUR 524.4

Kappa; Clone L1C1 (Concentrate)

A00113-C.1 0.1 ml
EUR 165.6

Recombinant human Interferon kappa

P1380 100ug Ask for price
Description: Recombinant protein for human Interferon kappa

Anti-immunoglobulin kappa antibody

PAab04295 100 ug
EUR 463.2

Recombinant Casein Kappa (CSN3)

4-RPJ331Bo01
  • EUR 679.10
  • EUR 304.80
  • EUR 2216.64
  • EUR 818.88
  • EUR 1517.76
  • EUR 530.40
  • EUR 5361.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Bovine Casein Kappa expressed in: E.coli

Recombinant Casein Kappa (CSN3)

4-RPJ331Hu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Casein Kappa expressed in: E.coli

Anti-NF kappa antibody

STJ94454 200 µl
EUR 236.4
Description: Rabbit polyclonal to NFRkappaB.

Anti-PP2 kappa antibody

STJ95197 200 µl
EUR 236.4
Description: Rabbit polyclonal to PP2Ckappa.

Anti-kappa-alpha antibody

STJ97440 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-alpha.

Anti-kappa beta antibody

STJ97539 200 µl
EUR 236.4
Description: IkappaB beta is a protein encoded by the NFKBIB gene which is approximately 37,7 kDa. IkappaB beta is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, toll-like receptor signalling pathways and the 4-1BB pathway. This protein falls under the NF-kappa-B inhibitor family, which inhibits NF-kappa-B by complexing with it and trapping it in the cytoplasm. Phosphorylation of serine residues on the protein marks it for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which then translocates to the nucleus to function as a transcription factor. IkappaB beta is expressed in the liver, lung, pancreas, nervous system and blood. STJ97539 was developed from clone 1F3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of IkappaB beta.

Anti-kappa beta antibody

STJ97540 200 µl
EUR 236.4
Description: Mouse monoclonal to IkappaB beta (8D11).

Anti-Actin-kappa antibody

STJ91470 200 µl
EUR 236.4
Description: Rabbit polyclonal to Actin-kappa.

Anti-DGK-kappa antibody

STJ92704 200 µl
EUR 236.4
Description: Rabbit polyclonal to DGK-kappa.

Anti-kappa-alpha antibody

STJ93782 200 µl
EUR 236.4
Description: IkappaB-alpha is a protein encoded by the NFKBIA gene which is approximately 35,6 kDa. IkappaB-alpha is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the TNFR1 pathway, 4-1BB pathway and toll-like receptor signalling pathways. This protein falls under the NF-kappa-B inhibitor family. It inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses it becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. IkappaB-alpha is expressed in adherent monocytes. Mutations in the NFKBIA gene may result in ectodermal dysplasia and leukorrhea. STJ93782 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IkappaB-alpha protein.

Anti-kappa-alpha antibody

STJ93783 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-alpha.

Anti-kappa-alpha antibody

STJ93784 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-alpha.

Anti-kappa-alpha antibody

STJ93785 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-alpha.

Anti-kappa-beta antibody

STJ93786 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-beta.

Anti-kappa-epsilon antibody

STJ93787 200 µl
EUR 236.4
Description: Rabbit polyclonal to IkappaB-epsilon.

Anti-kappa-beta antibody

STJ98186 100 µl
EUR 280.8
Description: Mouse monoclonal to IkappaB-beta.

Anti-kappa-alpha antibody

STJ98512 100 µl
EUR 280.8
Description: Mouse monoclonal to IkappaB-alpha.

anti-Kappa Opioid Receptor

YF-PA24281 50 ul
EUR 400.8
Description: Mouse polyclonal to Kappa Opioid Receptor

anti-Kappa light chain

YF-PA12641 50 ul
EUR 435.6
Description: Mouse polyclonal to Kappa light chain

anti-Kappa light chain

YF-PA12642 50 ug
EUR 435.6
Description: Mouse polyclonal to Kappa light chain

anti-Kappa light chain

YF-PA12643 100 ul
EUR 483.6
Description: Rabbit polyclonal to Kappa light chain

anti-Kappa light chain

YF-PA12644 100 ug
EUR 483.6
Description: Rabbit polyclonal to Kappa light chain

Kappa Light Chain Antibody

R20178-100UG 100ug
EUR 409

Kappa Light Chain Antibody

R20178BTN-50UG 50ug
EUR 409

Kappa Light Chain Antibody

R20178SAF-250UG 250ug
EUR 979

Kappa opioid receptor Antibody

R34964-100UG 100 ug
EUR 399

Kappa Light Chain Antibody

RQ5072 100ul
EUR 419

Kappa Light Chain Antibody

V2145-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2145-20UG 20 ug
EUR 219
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2145IHC-7ML 7 ml
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2145SAF-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2146-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2146-20UG 20 ug
EUR 219
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2146CF488-100T 100 Tests
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2146IHC-7ML 7 ml
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2146SAF-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2150-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2150-20UG 20 ug
EUR 219
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2150CF488-100T 100 Tests
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2150IHC-7ML 7 ml
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2150SAF-100UG 100 ug
EUR 499
Description: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2624-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2624-20UG 20 ug
EUR 219
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2624IHC-7ML 7 ml
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V2624SAF-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3135-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3135-20UG 20 ug
EUR 219
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3135IHC-7ML 7 ml
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3135SAF-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3148-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3148-20UG 20 ug
EUR 219
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3148IHC-7ML 7 ml
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3148SAF-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3302-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3302-20UG 20 ug
EUR 219
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3302SAF-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kappa Light Chain Antibody

V3591-100UG 100 ug
EUR 499
Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

While p53 activity is associated with the induction of apoptosis, stimulation of NF-kB has been shown to promote resistance to programmed cell death.

Megan

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