Dexmedetomidine Post-Conditioning Alleviates Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting High Mobility Group Protein BBNuclear Factor kappa B (NF-κB) Signaling Pathway.
BACKGROUND Cerebral ischemia-reperfusion injury is an important cause of death due to cerebrovascular accidents. increased research effort is needed to unravel the underlying mechanism of aggravation or reduction. In this study, the effects of dexmedetomidine post-conditioning in the HMGB1 / TLR4 / NF-kappaB signaling pathway in rat brain ischemia-reperfusion explored.
MATERIALS AND METHODS Ninety rats were randomly divided into 5 groups – groups of sham (Sham), a model group (I / R), a group of dexmedetomidine post-conditioning (Dex), high mobility group protein group B1 recombinant (rHMGB1), and HMGB1 + dexmedetomidine recombinant post-conditioning group (rHMGB1 + Dex) – with 18 rats in each group.
Longa levels, wet-dry weighing, TTC staining, HE staining and immunohistochemical staining was used to assess brain damage. ELISA, RT-PCR and Western blot analysis was performed to assess the expression of IL-1SS, TNF-alpha, IL-6, IL-8, HMGB1, TLR4 and NF-kappaB. RESULTS Compared with group I / R, neurological function score, the water content of the brain, the area of infarction, and the amount of COX-2 and IBA-1-positive cells in the group Dex significantly lower, accompanied by a decline in the function of HMGB1 / TLR4 / NF-kappaB pathway, alleviated inflammation and oxidative stress injury in brain tissue.
This trend reversed in the group mostly rHMGB1 and rHMGB1 + Dex group, but not in the Dex group. Furthermore, when compared with the group Dex, there was a significant increase of H₂O₂, MDA, NO, IL-1SS, TNF-alpha, IL-6, IL-8, HMGB1, TLR4, and p-P65 in the group rHMGB1 and rHMGB1 group + Dex, where a significant reduction of T-AOC, SOD, and p-IkappaBalpha also detected.
CONCLUSIONS Dexmedetomidine post-conditioning can relieve ischemia-reperfusion injury in rat brain by inhibiting pathways HMGB1 / TLR4 / NF-kappaB signaling.
Curcumin Relieves Lipopolysaccharide (LPS) -Activated Neuroinflammation through Modulation of miR-199b-5p / IκB kinase β (IKKβ) / Nuclear Factor Kappa B (NF-kB) pathway in microglia.
BACKGROUND Microglia stay in the spinal cord plays a key role in the onset, the development of post-spinal cord injury (SCI) neuroinflammation. Curcumin has been shown to exhibit a variety of anti-inflammatory activity and anti-tumor. The purpose of this study was to explore the effects of curcumin on inflammatory responses in lipopolysaccharide (LPS) -activated microglia and mechanisms.
MATERIALS AND METHODS The expression levels of phosphorylated-p65 (p-p65), tumor necrosis factor (TNF) -alpha, interleukin (IL) -1ß, and IkappaB kinase ß (IKKß) is checked by western blot assay. Expression of MiR-199b-5p detected by real-time quantitative polymerase chain reaction assay. Suspected binding site of miR-199b-5p in the 3’UTR IKKß predicted by bioinformatics, and direct interaction between miR-199b-5p and IKKß verified by dual-luciferase reporter assay and RNA-immunoprecipitation test.
RESULTS Curcumin significantly suppressed the inflammatory response induced by LPS with inactivation of nuclear factor kappa B (NF-kappaB) in microglial cells, which reflected a decrease in the level of p-p65, as well as pro-inflammatory mediators, including nitric oxide inducible nitric (iNOS), TNF-alpha, and IL-1SS. Additionally, curcumin increased the level of miR-199b-5p and decreased expression of activated microglia cells IKKß in.
Knockdown of miR-199b-5p or excess of IKKß reverse the inhibitory effect of curcumin on inflammatory responses and activation of NF-kappaB. MiR-199b-5p directly targeted IKKß and repressed expression. IKKß abolished silencing of miR-199b-5p-stimulate the production of inflammatory cytokines and activation of NF-kappaB.
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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20-abx174339 | Abbexa |
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Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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20-abx174340 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx128602-100l | Abbexa | 100 µl | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx128602-1ml | Abbexa | 1 ml | EUR 750 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx128602-200l | Abbexa | 200 µl | EUR 337.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx130205-100l | Abbexa | 100 µl | EUR 287.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx130205-1ml | Abbexa | 1 ml | EUR 812.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx130205-200l | Abbexa | 200 µl | EUR 362.5 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174339-100l | Abbexa | 100 µl | EUR 275 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174339-1ml | Abbexa | 1 ml | EUR 787.5 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174339-200l | Abbexa | 200 µl | EUR 350 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174340-100l | Abbexa | 100 µl | EUR 850 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174340-1ml | Abbexa | 1 ml | Ask for price |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
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abx174340-200l | Abbexa | 200 µl | Ask for price |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx270227-1ml | Abbexa | 1 ml | EUR 450 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx270227-200l | Abbexa | 200 µl | EUR 325 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx131781-100g | Abbexa | 100 µg | EUR 787.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx131781-20g | Abbexa | 20 µg | EUR 350 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx131781-5g | Abbexa | 5 µg | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx104350-100g | Abbexa | 100 µg | EUR 775 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx104350-20g | Abbexa | 20 µg | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
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abx104350-50g | Abbexa | 50 µg | EUR 350 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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APC057Hu01 | Cloud-Clone | 10ug | EUR 302 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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4-APC057Hu01 | Cloud-Clone |
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Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU55749-100ug | Biomatik Corporation | 100ug | EUR 936.1 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU55749-1mg | Biomatik Corporation | 1mg | EUR 4716.4 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU55749-50ug | Biomatik Corporation | 50ug | EUR 725.8 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2105163-001mg | MyBiosource | 0.01mg | EUR 235 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2105163-005mg | MyBiosource | 0.05mg | EUR 490 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2105163-01mg | MyBiosource | 0.1mg | EUR 750 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2105163-02mg | MyBiosource | 0.2mg | EUR 930 |
Active Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2105163-05mg | MyBiosource | 0.5mg | EUR 1800 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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20-abx270879 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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20-abx270989 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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abx270879-1ml | Abbexa | 1 ml | EUR 737.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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abx270879-200l | Abbexa | 200 µl | EUR 612.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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abx270989-1ml | Abbexa | 1 ml | EUR 1212.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
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abx270989-200l | Abbexa | 200 µl | EUR 737.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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20-abx270647 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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20-abx270757 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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abx270647-1ml | Abbexa | 1 ml | EUR 875 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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abx270647-200l | Abbexa | 200 µl | EUR 725 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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abx270757-1ml | Abbexa | 1 ml | EUR 1437.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
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abx270757-200l | Abbexa | 200 µl | EUR 875 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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20-abx270415 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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20-abx270525 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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abx270415-1ml | Abbexa | 1 ml | EUR 612.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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abx270415-200l | Abbexa | 200 µl | EUR 512.5 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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abx270525-1ml | Abbexa | 1 ml | EUR 1000 |
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
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abx270525-200l | Abbexa | 200 µl | EUR 612.5 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPC057Hu01 | Cloud-Clone | 10ug | EUR 168 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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4-RPC057Hu01 | Cloud-Clone |
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Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPC057Mu01 | Cloud-Clone | 10ug | EUR 176 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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4-RPC057Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPC057Ra01 | Cloud-Clone | 10ug | EUR 184 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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4-RPC057Ra01 | Cloud-Clone |
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Description: Recombinant Rat Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU52109-100ug | Biomatik Corporation | 100ug | EUR 517 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU52109-1mg | Biomatik Corporation | 1mg | EUR 2293.2 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU52109-50ug | Biomatik Corporation | 50ug | EUR 415.8 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU53947-100ug | Biomatik Corporation | 100ug | EUR 566.5 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU53947-1mg | Biomatik Corporation | 1mg | EUR 2511.6 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU53947-50ug | Biomatik Corporation | 50ug | EUR 455.4 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU43561-100ug | Biomatik Corporation | 100ug | EUR 542.3 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU43561-1mg | Biomatik Corporation | 1mg | EUR 2402.4 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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RPU43561-50ug | Biomatik Corporation | 50ug | EUR 435.6 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2018308-001mg | MyBiosource | 0.01mg | EUR 170 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2018308-005mg | MyBiosource | 0.05mg | EUR 305 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2018308-01mg | MyBiosource | 0.1mg | EUR 460 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2018308-02mg | MyBiosource | 0.2mg | EUR 560 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2018308-05mg | MyBiosource | 0.5mg | EUR 1065 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031260-001mg | MyBiosource | 0.01mg | EUR 170 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031260-005mg | MyBiosource | 0.05mg | EUR 295 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031260-01mg | MyBiosource | 0.1mg | EUR 445 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031260-02mg | MyBiosource | 0.2mg | EUR 540 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031260-05mg | MyBiosource | 0.5mg | EUR 1025 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031528-001mg | MyBiosource | 0.01mg | EUR 175 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031528-005mg | MyBiosource | 0.05mg | EUR 315 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031528-01mg | MyBiosource | 0.1mg | EUR 480 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031528-02mg | MyBiosource | 0.2mg | EUR 585 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
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MBS2031528-05mg | MyBiosource | 0.5mg | EUR 1110 |
Cat Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS062522-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Rat Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
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IRTRANKKT | Innovative research | each | EUR 790 |
Description: Rat Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
Duck Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS105319-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Cavy Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS060511-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Fish Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS075691-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Goat Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS066404-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Human Receptor Activator of Nuclear Factor Kappa B CLIA Kit |
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MBS8425869-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Receptor Activator of Nuclear Factor Kappa B CLIA Kit |
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MBS8426460-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx104600 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx129539 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx130179 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx131777 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx131778 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx131779 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx131780 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx270109 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx270204 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx270211 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx270212 | Abbexa |
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Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx174341 | Abbexa |
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Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx178216 | Abbexa |
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Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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20-abx178217 | Abbexa |
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) Antibody |
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abx237108-100ug | Abbexa | 100 ug | EUR 661.2 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx129539-100l | Abbexa | 100 µl | EUR 262.5 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx129539-1ml | Abbexa | 1 ml | EUR 687.5 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx129539-200l | Abbexa | 200 µl | EUR 325 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx130179-100l | Abbexa | 100 µl | EUR 262.5 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx130179-1ml | Abbexa | 1 ml | EUR 725 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx130179-200l | Abbexa | 200 µl | EUR 337.5 |
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx174341-100l | Abbexa | 100 µl | EUR 262.5 |
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx174341-1ml | Abbexa | 1 ml | EUR 712.5 |
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx174341-200l | Abbexa | 200 µl | EUR 325 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) Antibody |
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abx237108-100g | Abbexa | 100 µg | EUR 350 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270109-1ml | Abbexa | 1 ml | EUR 425 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270109-200l | Abbexa | 200 µl | EUR 300 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270204-1ml | Abbexa | 1 ml | EUR 425 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270204-200l | Abbexa | 200 µl | EUR 300 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270211-1ml | Abbexa | 1 ml | EUR 425 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270211-200l | Abbexa | 200 µl | EUR 300 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270212-1ml | Abbexa | 1 ml | EUR 425 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx270212-200l | Abbexa | 200 µl | EUR 300 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131777-100g | Abbexa | 100 µg | EUR 712.5 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131777-20g | Abbexa | 20 µg | EUR 325 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131777-5g | Abbexa | 5 µg | EUR 262.5 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131778-100g | Abbexa | 100 µg | EUR 775 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131778-20g | Abbexa | 20 µg | EUR 350 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131778-5g | Abbexa | 5 µg | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131779-100g | Abbexa | 100 µg | EUR 775 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131779-20g | Abbexa | 20 µg | EUR 350 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131779-5g | Abbexa | 5 µg | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131780-100g | Abbexa | 100 µg | EUR 775 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131780-20g | Abbexa | 20 µg | EUR 350 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx131780-5g | Abbexa | 5 µg | EUR 275 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx104600-100g | Abbexa | 100 µg | EUR 675 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx104600-20g | Abbexa | 20 µg | EUR 250 |
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
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abx104600-50g | Abbexa | 50 µg | EUR 312.5 |
Sheep Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS102488-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Sheep Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS102488-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Sheep Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS102488-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Sheep Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS102488-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Horse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS107632-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Horse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS107632-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Horse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS107632-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Horse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS107632-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Goose Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS106565-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS056312-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Mouse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS056312-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Mouse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS056312-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Mouse Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS056312-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS066686-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS066686-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS066686-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS066686-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Mouse receptor activator of nuclear factor kappa B ELISA Kit |
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ELA-E2057m | Nova Lifetech | 96tests | EUR 736 |
Camel Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS083100-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Camel Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS083100-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Camel Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS083100-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Camel Receptor Activator of Nuclear Factor Kappa B ELISA Kit |
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MBS083100-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Human Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
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IHURANKKT | Innovative research | each | EUR 733 |
Description: Human Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
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APA855Mu01 | Cloud-Clone | 10ug | EUR 310 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
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4-APA855Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
CONCLUSION Curcumin attenuated nerve inflammation induced by LPS through regulate miR-199b-5p / IKKß / NF-kappaB axis in microglia.